RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-101a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
dual-luciferase reporter assay
Target
RUNX1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-101 Protects Against Cardiac Remodeling Following Myocardial Infarction via Downregulation of Runt-Related Transcription Factor 1
Year
2019
Function
miR-101 plays a protective role against cardiac remodeling following myocardial infarction (MI) via inactivation of the runx1-dependent transforming growth factor beta1/smad family member 2 signaling pathway.